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How Does Priligy Work for Premature Ejaculation?

How Does Priligy Work for Premature Ejaculation? at The Kingston Pharmacy, Kingston upon Thames

A guide to how Priligy (dapoxetine) works, how effective it can be, and what to expect if treatment is recommended for premature ejaculation.

What Is Priligy?

Priligy is the brand name for dapoxetine, a prescription-only medication used to treat premature ejaculation in adult men aged 18 to 64 years. It belongs to a group of medicines called selective serotonin reuptake inhibitors (SSRIs). However, unlike SSRIs used to treat depression or anxiety, Priligy is designed to be taken only when needed before sexual activity.


Priligy is currently the only medication specifically licensed in the UK for the treatment of premature ejaculation. Before treatment is supplied, one of our pharmacists will assess whether Priligy is suitable for you based on your symptoms, medical history and current medications.

Priligy may be appropriate if you

  • Regularly ejaculate sooner than you would like
  • Feel you have little control over ejaculation
  • Experience frustration, distress or relationship difficulties because of premature ejaculation

How Does Priligy Work?

Priligy works by increasing the activity of serotonin, a chemical messenger found naturally in the brain and nervous system. Serotonin plays an important role in controlling ejaculation — by increasing its activity, Priligy helps delay the ejaculatory reflex and improve control during sexual activity.

  • Last longer before ejaculation
  • Feel more in control during sexual activity
  • Reduce anxiety around sexual performance
  • Improve overall sexual satisfaction

Although the medication can be very effective, results vary from person to person.

How Effective Is Priligy?

Clinical studies have shown that Priligy can significantly improve control over ejaculation for many men with premature ejaculation. The degree of improvement varies between individuals, but many men notice meaningful benefits when the medication is taken correctly.

Increased time before ejaculation
Greater confidence during sexual activity
Improved satisfaction for themselves and their partner
Reduced frustration and performance anxiety

Priligy works best when used as part of a broader approach that may also include behavioural techniques, lifestyle improvements and addressing any underlying psychological factors. During your consultation, our pharmacist can discuss what level of improvement you may realistically expect based on your circumstances.

How to Take Priligy

Priligy is taken when needed before sexual activity. The tablet should be swallowed whole with at least one full glass of water and can be taken with or without food. Because the medication can occasionally cause dizziness or fainting, staying well hydrated is important.

Dosing guidance

  • Starting dose: 30mg, taken 1 to 3 hours before anticipated sexual activity
  • If the 30mg dose is effective and well tolerated, continue at this dose
  • If the response is insufficient and side effects are acceptable, the dose may be increased to 60mg
  • Priligy should not be taken more than once in any 24-hour period

When Does Priligy Start Working?

One of the advantages of Priligy is that it is a fast-acting treatment. The medication is usually taken between 1 and 3 hours before sexual activity, which is when it reaches effective levels in the body. Many men notice an improvement the first time they use the medication, although individual responses can vary.


Because Priligy is rapidly absorbed and eliminated from the body, it does not need to be taken daily like some other medicines in the SSRI class. Our pharmacist will explain how and when to take the medication to help ensure the best possible results.

Potential Side Effects

Like all medicines, Priligy can cause side effects, although many men tolerate treatment well. These side effects are usually mild and temporary, and many men find that any effects become less noticeable as they become familiar with the treatment.

Nausea
Headache
Dizziness
Tiredness
Diarrhoea
Difficulty sleeping

  • Stay well hydrated to reduce the likelihood of dizziness or fainting
  • Avoid excessive alcohol
  • Follow the dosage instructions carefully

If side effects are persistent, troublesome or worsening, seek advice from a healthcare professional.

Who Can and Cannot Take Priligy?

Priligy is suitable for many men with premature ejaculation, but it is not appropriate for everyone. Before treatment is supplied, our pharmacists will assess your suitability carefully — this helps ensure that the medication is safe and appropriate for your individual circumstances.

Certain heart conditions
A history of fainting episodes
Significant liver problems
Certain antidepressants or other interacting medications
Specific mental health conditions

Priligy may not be suitable if any of the above apply. A consultation is always required before treatment is supplied.

Frequently Asked Questions

Will Priligy cure premature ejaculation?
Priligy is a treatment rather than a cure. It helps improve control over ejaculation while the medication is active in your system.
Do I need to take Priligy every day?
No. Priligy is designed to be taken only when needed before sexual activity, not as a daily medication.
Can I drink alcohol while taking Priligy?
Alcohol may increase certain side effects such as dizziness or fainting. For this reason, alcohol should be avoided or kept to a minimum when taking the medication.
Will Priligy affect my ability to get an erection?
Priligy is designed to treat premature ejaculation rather than erectile dysfunction. It does not directly improve erections, although some men find that improved confidence has a positive impact on their sexual experience.
How do I know if Priligy is right for me?
The best way to determine suitability is through a consultation. Our pharmacists can assess your symptoms, medical history and current medications before recommending treatment.

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