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Bexsero® Explained: How Effective Is the Meningitis B Vaccine?

Bexsero® Explained: How Effective Is the Meningitis B Vaccine? at The Kingston Pharmacy, Kingston upon Thames

A guide to the MenB vaccine used in the UK, how it works, who it is designed to protect, and what to expect if you’re considering vaccination.

What Is Bexsero®?

Bexsero® is the meningitis B (MenB) vaccine used in the UK to help protect against meningococcal group B bacteria — which can cause serious infections including meningitis and septicaemia (blood poisoning).


Since its introduction into the UK childhood vaccination programme, Bexsero® has played an important role in reducing cases of MenB disease in young children. The vaccine is also available privately for older children, teenagers, and adults who wish to receive protection against meningococcal B disease.

What Does the MenB Vaccine Protect Against?

Meningococcal disease can be caused by several different groups of bacteria. Bexsero® is designed specifically to help protect against meningococcal group B bacteria — one of the most common causes of invasive meningococcal disease in the UK.


The vaccine does not protect against every type of meningococcal bacteria. It does not replace the MenACWY vaccine, which protects against meningococcal groups A, C, W and Y. This is why some individuals may benefit from receiving both vaccines.

How Does Bexsero® Work?

Like all vaccines, Bexsero® works by training the immune system to recognise specific components of meningococcal B bacteria. After vaccination, the body produces protective antibodies. If the immune system encounters meningococcal B bacteria in the future, these antibodies can respond more quickly and help prevent serious illness from developing.

Important to understand

  • The vaccine cannot cause meningitis
  • It prepares the body’s natural defences to recognise and fight the bacteria if exposure occurs
  • Protection develops in the weeks following vaccination

How Effective Is the MenB Vaccine?

No vaccine can provide 100% protection, but Bexsero® has been shown to provide protection against the majority of meningococcal B strains responsible for disease in the UK.

~88%
of MenB strains circulating in England and Wales are covered by the Bexsero® vaccine, based on published surveillance data

Since its introduction into the routine childhood immunisation programme in 2015, the vaccine has had a significant impact on reducing MenB cases. UK surveillance data has shown substantial reductions among vaccine-eligible children, with hundreds of cases estimated to have been prevented since the programme began.


This strong evidence of effectiveness is one of the key reasons Bexsero® was added to the national childhood vaccination programme and continues to be recommended for those at increased risk. While meningitis B remains uncommon, the severity of the disease means that many people choose vaccination for the additional protection it provides.

Who Should Consider MenB Vaccination?

The MenB vaccine may be worth considering for people who want protection against meningococcal B disease, particularly if they have not previously received vaccination.

  • Teenagers and young adults
  • University students
  • Individuals living in shared accommodation
  • People born before MenB vaccination became part of the routine childhood schedule
  • Those looking for additional protection against meningococcal disease

Many parents also choose MenB vaccination for older children who were not eligible when the vaccine was first introduced.

What Are the Side Effects of Bexsero®?

Most people tolerate Bexsero® well. Like all vaccines, side effects can occur, but they are usually mild and temporary — and are typically a sign that the immune system is responding to the vaccine. Most side effects settle within a few days without any treatment.

Pain, redness or swelling at the injection site
Tiredness
Headache
Muscle aches
Mild fever
Feeling generally unwell for a short period after vaccination

Serious side effects are rare. If you have concerns about vaccine suitability, a healthcare professional can discuss these with you before vaccination.

What to Do Next

Meningitis B is a rare but potentially serious disease that can affect people of all ages. Vaccination with Bexsero® provides protection against the most common MenB strains responsible for disease in the UK and is often chosen by students, young adults, and those seeking additional protection against meningococcal infection.


If you would like to learn more about MenB vaccination or discuss whether Bexsero® is suitable for you or a family member, our team at The Kingston Pharmacy can help. Book an appointment today to receive personalised advice and discuss your vaccination options.

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